Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 13, Pages 3867-3869Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10183h
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- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [471, 22750143]
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The compound 2-[(1E)-2-(1H-pyrrol-2-yl)ethenyl]-quinoxaline (PQX) is a promising fluorescent chromophore for the estimation of protein binding site polarity, due to its full-color solvatochromic fluorescence. A linear relationship was obtained between the peak emission wavenumber and E(T)(N) (normalized solvent polarity). The BSA binding site polarity was estimated from the solvatochromic plot.
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