Biopolymers phase separation monitored by a plasmonic sensor

We report here a real-time study of interactions induced phase separation between beta-lactoglobulin (BLG) and Acacia gum (AG) by analyzing the localized surface plasmon resonance of silver nanoparticles. We showed that the binding of BLG to AG is accompanied by refractive index changes, in relation with optical properties and structural changes of the complexes formed.