Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 15, Pages 4526-4528Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05580h
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Funding
- EPSRC
- Royal Society
- Bristol Chemical Synthesis Doctoral Training Centre
- EPSRC [EP/F027222/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/F027222/1] Funding Source: researchfish
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A general and efficient chromatography-free ionic-liquid-supported catch-and-release strategy for oligosaccharide synthesis (ICROS) is reported. The methodology is compatible with current glycosylation strategies and amenable to protecting group manipulations. A series of beta-(1 -> 6) and beta-(1 -> 2)-linked glycan structures have been prepared to showcase the versatility of the strategy.
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