Journal
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
Volume 64, Issue 3, Pages 548-+Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/MMBR.64.3.548-572.2000
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Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R37GM019698, R01GM019698, R55GM047461, R29GM047461] Funding Source: NIH RePORTER
- NIGMS NIH HHS [GM47461, GM19698, R37 GM019698, R01 GM019698] Funding Source: Medline
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Endospores of Bacillus spp., especially Bacillus subtilis, have served as experimental models for exploring the molecular mechanisms underlying the incredible longevity of spores and their resistance to environmental insults. In this review we summarize the molecular laboratory model of spore resistance mechanisms and attempt to use the model as a basis for exploration of the resistance of spores to environmental extremes both on Earth and during postulated interplanetary transfer through space as a result of natural impact processes.
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