Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 35, Pages 9876-9878Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13122b
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Funding
- Ministry of Knowledge Economy (MKE) [201010038683]
- Ministry of Education, Science and Technology [2009-0080602]
- KRIBB Research Initiative
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By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.
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