Journal
CHEMICAL SOCIETY REVIEWS
Volume 29, Issue 5, Pages 347-357Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/a908114c
Keywords
-
Categories
Ask authors/readers for more resources
Organoselenium compounds find applications in organic synthesis, materials synthesis, ligand chemistry and biologically relevant processes. This review deals with the use of various synthetic organoselenium compounds as mimics of glutathione peroxidase (GPx), a selenoenzyme which catalyses the reduction of a variety of hydroperoxides and protects the cell membranes from oxidative damage. The mechanism by which these compounds catalyse the reduction of peroxides is also reviewed. The cyclic selenenamides and diselenides with suitably positioned substituents exert their catalytic activity by a mechanism similar to that of the natural enzyme.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available