Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 8, Pages 2249-2251Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04903d
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Funding
- European Community
- Engineering and Physical Sciences Research Council (EPSRC), UK
- ERC
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Two complementary formats for kinase inhibitor screening are presented in which peptide-modified gold nanoparticles are enzymatically phosphorylated and rapidly aggregate on a surface or in solution by action of phosphospecific antibodies. The simple and rapid colourimetric response of the assays makes them an attractive approach for drug-screening applications.
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