4.7 Article

Antibody-functionalized SERS tags with improved sensitivity

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 31, Pages 8784-8786

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12659h

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Funding

  1. Army Research Office
  2. NSF Center for Chemistry at the Space-Time Limit [CHE-0802913]
  3. Spanish National Research Council (CSIC) of Spain
  4. Division Of Materials Research [0843934] Funding Source: National Science Foundation

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Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain suitable surface-bound recognition elements. Proper control of the interaction between nanoparticles within the assemblies is critical for achieving this performance.

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