4.7 Article

Target recycling amplification for sensitive and label-free impedimetric genosensing based on hairpin DNA and graphene/Au nanocomposites

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 48, Pages 12798-12800

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14902d

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Funding

  1. National Natural Science Foundation of China [20905062, 20675064]
  2. Natural Science Foundation of Chongqing City [CSTC-2009BB5052]
  3. State Key Laboratory of Electroanalytical Chemistry [SKLEAC2010009]
  4. China Postdoctoral Science Foundation [20090460715, 201003305]
  5. Scientific Research Foundation for the Returned Overseas Chinese Scholars
  6. Southwest University [SWUB2008078]

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The presence of exonuclease III leads to direct recycling and reuse of the target DNA, which in turn results in substantial signal amplification for highly sensitive, label-free impedimetric detection of specific DNA sequences.

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