Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 2, Pages 686-688Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04303f
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Funding
- Science Foundation Ireland (SFI)
- TCD
- Irish Research Council for Science, Engineering and Technology (IRCSET)
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The quaternarized pdppz derivative 1 was shown to bind strongly to DNA with concomitant changes in its ground and excited state photophysical properties. Furthermore, the compound also showed rapid cellular uptake, and induced apoptosis upon light irradiation in various cancer cell lines after 24 hours of incubation.
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