Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 7, Pages 2140-2142Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04515b
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Funding
- Research Grants Council of Hong Kong [CityU 101607]
- Area of Excellence Scheme [AoE/P-10/01]
- ITF-Tier 2 [ITS/134/09FP]
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A nitridoosmium(VI) complex [Os-VI(N)(sap)(OH2)Cl] (H(2)sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S-and G2/M-phase arrest and forms a stable adduct with dianionic 5'-guanosine monophosphate.
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