4.7 Article

Light-induced cytotoxicity of a photochromic spiropyran

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 39, Pages 11020-11022

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13561a

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Funding

  1. Swedish Research Council (VR) [2007-5520, 622-2010-280]
  2. European Research Council (ERC) [FP7/2007-2013, 203952]
  3. Swedish Foundation for Strategic Research
  4. Carl Trygger Foundation for Scientific Research

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In this work we present a novel water soluble spiropyran photoswitch that can be photonically activated inside live cells from a form that has no significant effect on the cellular survival to a form that induces a dramatic toxic response.

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