Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 33, Pages 9321-9323Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13213j
Keywords
-
Categories
Funding
- European Research Council [ERC 201749]
- Institut Univervsitaire de France (IUF)
Ask authors/readers for more resources
We report the synthesis of a nucleic acid-encoded carbohydrate library, its combinatorial self-assembly into 37 485 pairs and a screen against DC-SIGN leading to the identification of consensus ligand motifs. A prototypical example from the selected pairs was shown to have enhanced binding. A dendrimer incorporating the selected motifs inhibited gp120's binding to dendritic cells with higher efficiency than mannan.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available