4.7 Article

Facile synthesis of alumina hollow spheres for on-plate-selective enrichment of phosphopeptides

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 18, Pages 5334-5336

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05524g

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Funding

  1. National Natural Science Foundation of China [20875017]
  2. Technological Innovation Program of Shanghai [09JC1401100]
  3. National Basic Research Priorities Program [2007CB914100/3]
  4. Shanghai Leading Academic Discipline Project [B109]

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Alumina hollow spheres were synthesized, spotted and sintered on a stainless-steel plate. These spots were used to selectively capture phosphopeptides from peptide mixtures and the captured target peptides could be analyzed by MALDI-MS. This provides a fast and efficient on-plate selective enrichment method for phosphopeptides investigation.

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