4.7 Article

An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 16, Pages 4733-4735

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10240k

Keywords

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Funding

  1. National Natural Science Foundation of China [20905062, 20675064]
  2. Natural Science Foundation of Chongqing City [CSTC-2009BB5052]
  3. State Key Laboratory of Electro-analytical Chemistry [SKLEAC2010009]
  4. China Postdoctoral Science Foundation [20090460715, 201003305]
  5. Fundamental Research Funds for the Central Universities [XDJK2009B013]
  6. Chongqing University of Technology

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One-spot signal-on and simultaneous electronic detection of lysozyme and adenosine is achieved based on target-induced release of aptamers and back-filling hybridization of the resulting single stranded DNAs with redox-tags conjugated aptamers.

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