4.7 Article

A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 19, Pages 5593-5595

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11223f

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Funding

  1. National Natural Science Foundation of China [20802075, 21042006]

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An effective double Michael reaction has been disclosed to access spirocyclic oxindoles in high yields (up to 98%) and excellent enantioselectivities (up to 98% ee).

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