4.7 Article

Ionic liquid-assisted transdermal delivery of sparingly soluble drugs

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 9, Pages 1452-1454

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b907462g

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan

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We report the first successful application of a novel IL-assisted non-aqueous microemulsion stabilized by a blend of two nontoxic surfactants, polyoxyethylene sorbitan monooleate (Tween-80), and sorbitan laurate (Span-20) for transdermal delivery of acyclovir, which is insoluble or sparingly soluble in water and most common organic liquids.

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