4.7 Article

Carbon nanotube-DNA hybrid fluorescent sensor for sensitive and selective detection of mercury(II) ion

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 9, Pages 1476-1478

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b921191h

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Funding

  1. National Natural Science Foundation of China [20735003]
  2. 973 Project [2009CB930100, 2010CB933600]
  3. Chinese Academy of Sciences [KJCX2 YW HO9]

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Mercury ion (Hg2+) is able to specifically bind to the thymine-thymine (T-T) base pair in a DNA duplex and single-walled carbon nanotubes (SWNTs) can effectively quench fluorescence of the dye tethered to the DNA, which enables fluorescent detection of Hg2+ in aqueous solution with high selectivity and sensitivity.

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