4.7 Article

Total synthesis of largamide H

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 1, Pages 153-155

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b921000h

Keywords

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Funding

  1. Hong Kong Research Grants Council [PolyU 5407/06M]
  2. Shenzhen Bureau of Science, Technology and Information [08systs-01, JC200903160367A]
  3. Shenzhen Foundation for RD [SZKJ-2007011, SY2008063 00179A]
  4. Nanshan Science Technology [NANKEYUAN2007019]
  5. NSF of GuangDong Province [8451805704000656]

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Total synthesis of largamide H has been completed, utilising the oxidative elimination reaction of enantiomerically pure 2-amino3-(phenylselenyl) butanoic acid residues to stereospecifically install both (Z)- and (E)-2,3-dehydro-2-aminobutanoic moieties.

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