Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 38, Pages 7247-7249Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01940b
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Funding
- Universite Paul Cezanne
- CNRS (iSm2-UMR 6263)
- Ministere de l'Enseignement Superieur et de la Recherche
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A new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity. This one-pot process combines an enantioselective organocatalytic Michael addition with a highly diastereoselective [3+2]-cycloaddition- fragmentation step.
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