4.7 Article

Decarboxylative homocoupling of (hetero) aromatic carboxylic acids

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 43, Pages 8276-8278

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01943g

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Funding

  1. EPSRC
  2. Royal Society
  3. QMUL
  4. Conseil regional de Picardie

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A variety of hetero(aromatic) carboxylic acids are shown to undergo decarboxylative homocoupling, mediated by a Pd/Ag system. This novel methodology for the synthesis of symmetrical biaryls avoids the use of haloarenes and organometallic compounds as starting materials.

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