4.7 Article

Asymmetric PPCys: Strongly fluorescing NIR labels

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 29, Pages 5289-5291

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00359j

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Funding

  1. Bioimaging Center of the University of Konstanz
  2. [SFB 767]

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By a stepwise synthesis strategy biofunctionalized Pyrrolopyrrole Cyanines (PPCy) with an asymmetric substitution pattern were obtained. These exhibit extremely strong and narrowband NIR absorption and fluorescence. Internalization of a peptide bound PPCy is demonstrated using live cell microscopy.

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