4.7 Article

A highly selective lead sensor based on a classic lead DNAzyme

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 22, Pages 3896-3898

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b926910j

Keywords

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Funding

  1. US Department of Energy [DE-FG02-08ER64568]
  2. National Institutes of Health [ES016865]
  3. National Science Foundation [CTS-0120978, DMI-0328162]
  4. NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [R01ES016865] Funding Source: NIH RePORTER

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A catalytic beacon sensor for Pb2+ has been developed based on the first DNAzyme discovered in the field, and such a sensor has shown a much higher metal ion selectivity (40 000 times) than the previously reported Pb2+ sensor based on 8-17 DNAzyme and thus is suitable for a wider range of practical applications.

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