Visual and light scattering spectrometric detections of melamine with polythymine-stabilized gold nanoparticles through specific triple hydrogen-bonding recognition

Melamine can be sensitively detected in aqueous medium through its selective interaction with polythymine (polyT(n)) modified gold nanoparticles (AuNPs) by forming triple H-bonds, which results in aggregation of the polyT(n)-stabilized AuNPs, displaying variations of localized plasmon resonance features such as colour change from red to purple and enhanced localized surface plasmon resonance light scattering (LSPR-LS) signals.