4.7 Article

G-quadruplex facilitated turn-off fluorescent chemosensor for selective detection of cupric ion

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 39, Pages 7385-7387

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc01695k

Keywords

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Funding

  1. National Natural Science Foundation of China [20905056, 20735003]
  2. 973 Project [2009CB930100, 2010CB933600]

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A simple turn-off fluorescent method was utilized to quantitatively detect Cu(II) which can selectively quench fluorescent dye molecules. Addition of DNA G-quadruplex into the solution significantly magnifies the discrimination, lowers the limit of detection and broadens the linear response range.

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