4.7 Article

Polymer-peptide chimeras for the multivalent display of immunogenic peptides

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 13, Pages 2188-2190

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b924112d

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Funding

  1. University of Sydney
  2. ARC [DP0986632]

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Chimeras of poly(n-isopropyl acrylamide) and immunogenic peptides from the cancer-associated glycoprotein MUC1 were synthesised using a combination of solid-phase peptide synthesis, RAFT polymerisation and copper-catalysed alkyne-azide cyclo-addition reactions.

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