4.7 Article

Enantioselective construction of allylic phosphine oxides through substitution of Morita-Baylis-Hillman carbonates with phosphine oxides

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 16, Pages 2856-2858

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b926037d

Keywords

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Funding

  1. NSFC [20525206, 20932003, 90813012, 20621091]
  2. National S&T Major Project of China [2009ZX09503-017]

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The asymmetric organocatalytic allylic substitution reaction of MBH carbonates with phosphine oxides has been developed. This organocatalytic approach constitutes an easy and efficient method for the direct preparation of allylic phosphine oxides in high enantioselectivities.

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