Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 38, Pages 7202-7204Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc03142a
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Funding
- National Nature Science Foundation of China [20673059, 20573056, 21073063]
- Nature Science Keystone Foundation of Shanghai [08jc1408100]
- Fundamental Research Funds for the Central Universities, China [WK0913002]
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A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO(2). The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to the photothermic effects inducing phase transition of the liposome rather than destruction of the liposome structure.
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