Journal
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
Volume 62, Issue -, Pages 711-730Publisher
BLACKWELL PUBL LTD
DOI: 10.1111/1467-9868.00259
Keywords
counting process; empirical process; intensity function; martingale; partial likelihood; Poisson process
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The counting process with the Cox-type intensity function has been commonly used to analyse recurrent event data. This model essentially assumes that the underlying counting process is a time-transformed Poisson process and that the covariates have multiplicative effects on the mean and rate functions of the counting process. Recently, Pepe and Cai, and Lawless and coworkers have proposed semiparametric procedures for making inferences about the mean and rate functions of the counting process without the Poisson-type assumption. In this paper, we provide a rigorous justification of such robust procedures through modern empirical process theory. Furthermore, we present an approach to constructing simultaneous confidence bands for the mean function and describe a class of graphical and numerical techniques for checking the adequacy of the fitted mean and rate models. The advantages of the robust procedures are demonstrated through simulation studies. An illustration with multiple-infection data taken from a clinical study on chronic granulomatous disease is also provided.
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