Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 41, Pages 7760-7762Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc02811h
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- DFG
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Site-directed mutagenesis based on the crystal structure of AurF, a nitro group forming monooxygenase from Streptomyces thioluteus, revealed that AurF variants are capable of selectively transforming guanidyl- and amidinyl-substituted anilines into the corresponding nitro compounds. Our results provide new insights into the biochemical basis of regioselective N-oxygenation.
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