Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 25, Pages 4472-4474Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c000254b
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Funding
- University of Massachusetts, Dartmouth
- National Institutes of Health [1 R21 AT002743-02]
- NATIONAL CENTER FOR COMPLEMENTARY &ALTERNATIVE MEDICINE [R21AT002743] Funding Source: NIH RePORTER
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A profluorescent probe that has no fluorescent response to H2O2, iron or copper ions but can be readily activated in the presence of both H2O2 and Fe (or Cu) ion has been developed; the probe is capable of detecting oxidative stress promoted by Fe (or Cu) and H2O2 (i.e. the Fenton reaction conditions) in living cells.
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