4.7 Article

Are there single-well hydrogen bonds in pyridine-dichloroacetic acid complexes?

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 3, Pages 481-483

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b917765e

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Funding

  1. NSF [CHE07-42801]

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The (18)O-induced isotope shifts in (13)C NMR spectra of 1 : 1 complexes of Cl(2)CHC(18)O(2)H with a series of substituted pyridines in CD(2)Cl(2) at low temperature reach a maximum when the acidities of the hydrogen-bond donors are matched, consistent with a mixture of tautomers, and with no drop that would indicate a single-well H-bond.

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