4.7 Article

Domino allylic amination/Sonogashira/heterocyclisation reactions: palladium-catalysed three-component synthesis of pyrroles

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 28, Pages 5157-5159

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00500b

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Three-component reactions with 3,4-diiodoalk-2-enoic derivatives, primary amines, and terminal alkynes proceeded to give trisubstituted pyrroles in fair to good yields in the presence of palladium and copper catalysts under mild reaction conditions.

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