4.7 Article

exo-Selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkylidene malonates catalyzed by AgOAc/TF-BiphamPhos

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 10, Pages 1727-1729

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b919625k

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Funding

  1. National Natural Science Foundation of China
  2. SRFD
  3. Wuhan University

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The first exo-selective asymmetric 1,3-dipolar cycloaddition of alkylidene malonates with azomethine ylides catalyzed by AgOAc/TF-BiphamPhos has been reported in good yields and good to excellent enantio-/diastereoselectivities.

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