Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 39, Pages 7379-7381Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc02092c
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Funding
- European Union [HEALTH-2007-201587]
- CNRS
- University of Trieste
- Italian Ministry of Education MIUR [RBIN04HC3S]
- School of Pharmacy, University of London
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We have covalently grafted aptamers onto carboxylated carbon nanotubes to design a novel vector system that can easily translocate into the cytosol of different cell types independent of receptor-mediated uptake. We propose the use of carbon nanotubes for the efficient intracellular delivery of biologically active aptamers for potential therapeutic applications.
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