Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 19, Pages 3351-3353Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c001314e
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Funding
- Sloan Fellowship
- NIH [R01 GM084254]
- UCSB
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM084254] Funding Source: NIH RePORTER
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A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.
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