Journal
CHEMICAL COMMUNICATIONS
Volume 46, Issue 48, Pages 9200-9202Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc03600e
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Funding
- Ministry of Education, Culture, Science, Sports and Technology of Japan
- Japan Society for the Promotion of Science (JSPS)
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We have successfully achieved transcutaneous immunization without the use of any skin pre-treatment or immune-stimulant adjuvant by applying a solid-in-oil (S/O) nanodispersion: an oil-based nanodispersion of antigens coated with hydrophobic surfactant molecules. This finding indicates that the S/O nanodispersion has great promise for effective transcutaneous vaccination.
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