4.7 Article

A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 31, Pages 5710-5712

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00477d

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Funding

  1. National Nature Science Foundation of China [20975012, 60978034, 20953002]
  2. 111 Project [B07012]

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A naphthalimide-based colorimetric fluorescent probe containing a disulfide group was designed and synthesized, which could detect the physiological level of GSH quantitatively by a ratiometric fluorescence method and was successfully applied to the imaging of thiols in living HeLa cells.

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