4.7 Article

Synthesis of chiral tertiary trifluoromethyl alcohols by asymmetric nitroaldol reaction with a Cu(II)-bisoxazolidine catalyst

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 42, Pages 8026-8028

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc02378g

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Funding

  1. National Science Foundation [CHE-0848301]

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A highly enantioselective and diastereoselective copper(II)-bisoxazolidine catalyzed nitroaldol reaction with aliphatic and aromatic trifluoromethyl ketones is described.

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