4.7 Article

Colorimetric detection of microRNA and RNase H activity in homogeneous solution with cationic polythiophene derivative

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 22, Pages 3172-3174

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b904579a

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Funding

  1. National Natural Science Foundation of China [20675023, 20875021]

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A colorimetric assay for convenient detection of miRNA and RNase H activity was established in a homogeneous and label-free manner based on conformational and colorimetric changes of a polythiophene derivative (PMNT) in the duplex of DNA/PMNT and triplex of DNA/miRNA/PMNT.

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