4.7 Article

Asymmetric generation of fluorine-containing quaternary carbons adjacent to tertiary stereocenters: uses of fluorinated methines as nucleophiles

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 15, Pages 2044-2046

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b823184b

Keywords

-

Funding

  1. National University of Singapore
  2. Ministry of Education (MOE) of Singapore [R-143-000-362-112]

Ask authors/readers for more resources

Organocatalytic asymmetric Michael reactions of fluorinated nucleophiles with nitroolefins catalyzed by Cinchona alkaloid-derived thiourea catalysts generated the desired Michael products containing vicinal fluorinated quaternary and tertiary chiral centers with exceptional enantioselectivity.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available