4.7 Article

An ultrasensitive electrochemical turn-on label-free biosensor for Hg2+ with AuNP-functionalized reporter DNA as a signal amplifier

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 37, Pages 5633-5635

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b911163h

Keywords

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Funding

  1. National Natural Science Foundation of China [20505008, 20605007, 20675028, 20775023]
  2. 973 National Key Basic Research Program of China [2007CB310500, NCET-07-0272]

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A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNA thymine bases (T-Hg2+ -T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.

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