4.7 Article

Silica nanoparticle supported lipid bilayers for gene delivery

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 34, Pages 5100-5102

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b911472f

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Funding

  1. USA NIH through the NIH Roadmap for Medical Research, DOE Office of Science and Air Force Office of Scientific Research
  2. NATIONAL EYE INSTITUTE [PN2EY016570] Funding Source: NIH RePORTER

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Silica nanoparticle supported cationic lipids can effectively bind plasmid DNAs and transfect mammalian cells with an efficiency that depends on both the particle size and lipid composition; here the gene delivery and expression process has been confirmed by confocal fluorescence microscopy.

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