4.7 Article

Copper-catalyzed aerobic phosphonation of sp3 C-H bonds

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 27, Pages 4124-4126

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b905275e

Keywords

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Funding

  1. Canada Research Chair (Tier 1) foundation
  2. NSERC
  3. Canada foundation for Innovation
  4. McGill University

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An efficient cross-dehydrogenative-coupling (CDC) between sp(3) C-H and H-P bonds was developed using copper salt as catalyst and molecular oxygen as terminal oxidant; this new methodology provides an easy access to biologically important alpha-aminophosphonates.

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