4.7 Article

An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 39, Pages 5838-5840

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b907762f

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Funding

  1. Korea government (MOST) [R01-2007-000-11851-0]
  2. Brain Korea 21 (BK21)
  3. Center for Ultramicrochemical Process Systems (CUPS)

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An ultrasensitive DNAzyme-based colorimetric DNA detection strategy was developed by utilizing gold nanoparticles modified with both peroxidase-mimicking DNAzymes and capture DNAs and magnetic nanoparticles modified with another capture DNAs, with a detection limit for a model Chlamydia gene of 50 fM.

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