4.7 Article

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromones via novel variants of Biginelli reaction

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 19, Pages 2768-2770

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b901112a

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Funding

  1. NSFC of China [20775069]
  2. National Ministry of Education of China [NCET-06-0520]

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A novel and facile cascade Biginelli-like assembly employing enaminone, aldehyde and urea/thiourea has been developed, which provides a highly chemo- and regioselective synthesis of new dihydropyrimidinones, 1,3-thiazines and chromones by altering particular functional groups in the reactants.

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