Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 17, Pages 2284-2286Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b820001g
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Funding
- National University of Singapore [ARF R-279-000-197-112/113, YIA R-279-000-234-123]
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Surface charge switch of a 6-carboxyfluorescein (FAM) labeled lysozyme aptamer from negative to positive upon lysozyme binding triggers fluorescence resonance energy transfer (FRET) between an anionic conjugated polymer and the aptamer, which provides a convenient method for lysozyme detection in biological media with high sensitivity and selectivity.
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