4.7 Article

Effect of chirality of L/D-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(α-aminoacid)-thymidine dimers

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 43, Pages 6646-6648

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b913546d

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Funding

  1. UGC, New Delhi
  2. Wellcome Trust, UK
  3. CSIR, New Delhi

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The chirality of the amide linker in dimer blocks was found to have a profound effect on the orientation of base stacking interactions as studied by CD and NMR spectroscopy.

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