4.7 Article

Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 48, Pages 7482-7484

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b901889a

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Funding

  1. Cancer Research UK [C129/A4489]
  2. European COST action [MP0802]
  3. University of Liege [FRSD 08/10]
  4. FNRS [CC 1.5.286.09.F]

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Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.

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