4.7 Article

Polymer/silica hybrid hollow nanospheres with pH-sensitive drug release in physiological and intracellular environments

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 19, Pages 2718-2720

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b900751b

Keywords

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Funding

  1. National Natural Science Foundation of China [50603008, 50625311, 5057301]
  2. National 863 Projects [2007AA100704]
  3. Cultivation Fund of the Key Scientific and Technical Innovation Project, Ministry of Education of China [707028]

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Hybrid hollow nanospheres of chitosan-silica templated by chitosan-poly(acrylic acid) nanoparticles are fabricated in a complete aqueous system, which provide a pH-sensitive switch in physiological and sub-cell environments for the release of loaded drug.

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